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Torped (Cefotaxime) is indicated for the treatment of the following infections either before the infecting organism has been identified or when caused by bacteria of established sensitivity. Respiratory Tract Infections such as acute or chronic bronchitis, bacterial pneumonia, infected bronchiectasis, lung abscess and postoperative chest infections. Urinary Tract Infections such as acute and chronic pyelonephritis, cystitis and asymptomatic bacteriuria. Soft-tissue Infections such as cellulitis, peritonitis and wound infections. Bone and Joint Infections such as osteomyelitis, septic arthritis. Obstetric and gynaecological infections such as pelvic inflammatory disease. Gonorrhoea particularly when penicillin has failed or is unsuitable. Septicaemia Other Bacterial Infections Meningitis and other sensitive infections suitable for parenteral antibiotic therapy. Prophylaxis The administration of Cefotaxime prophylactically may reduce the incidence of certain post operative infections in patients undergoing surgical procedures that are classified as contaminated or potentially contaminated or in clean operation where infection would have serious effects.

Adults The recommended dosage for mild to moderate infections is 1g every 12 hourly. However, dosage may be varied according to the severity of infection, sensitivity of causative organisms and condition of the patient. In severe infections dosage may be increased up to 12 g daily given in 3 or 4 divided doses. For infections caused by sensitive Pseudomonas spp. daily doses of greater than 6 g will usually be required. Children The usual dosage range is 100-150 mg/kg/day in 2 to 4 divided doses. However, in very severe infections doses of up to 200 mg/kg/day may be required. Neonates The recommended dosage is 50 mg/kg/day in 2 to 4 divided doses. In severe infections 150-200 mg/kg/day, in divided doses, have been given. Dosage in gonorrhoea A single injection of 1 g may be administered intramuscularly or intravenously. Dosage in renal impairment Because of extra-renal elimination, it is only necessary to reduce the dosage of Cefotaxime in severe renal failure (GFR<5 ml/min = serum creatinine approximately 751 micromol/litre). After an initial loading dose of 1 g, daily dose should be halved without change in the frequency of dosing. In all other patients, dosage may require further adjustment according to the course of infection and the general condition of the patient. route - IM - 250 mg 2 ml, 500 mg 2 ml, 1 gm 3 ml route - IV - 250 mg 2-5 ml, 500 mg 2-10 ml, 1 gm 4-10 ml

Torped (Cefotaxime) is contraindicated in patients who have shown hypersensitivity to cefotaxime or the cephalosporin group of antibiotics.